Telomere length: biological marker of cellular vitality, aging, and health-disease process

نویسندگان

چکیده

SUMMARY The aging process occurs due to the decline of vital physiological functions and adaptability body, being influenced by genetics lifestyle. With advances in genetics, biological can be calculated telomere length. Telomeres are regions at ends chromosomes that play a role maintenance integrity DNA. aging, shortening occurs, causing cellular senescence. Several studies show shorter telomeres associated with acute chronic diseases, stress, addictions, intoxications. Even current COVID-19 pandemic, is proposed as marker severity individuals infected severe respiratory syndrome coronavirus 2 (SARS-CoV-2). On other hand, healthy lifestyle habits increase length balance various functions, preventing diseases.

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Telomere length: a marker of disease susceptibility?

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ژورنال

عنوان ژورنال: Revista Da Associacao Medica Brasileira

سال: 2021

ISSN: ['2255-4823']

DOI: https://doi.org/10.1590/1806-9282.67.02.20200655